- Family history of breast and/or ovarian cancer
- Bilateral or multiple breast cancers
- Diagnosed with both breast and ovarian cancer
- Early onset breast cancer (under 50 years of age)
- Male breast cancer within family
BRCA1 and BRCA2 gene testing can help you to prevent developing future cancer
Breast Cancer is very common among Canadians. The Canadian Breast Cancer Foundation reported in 2014 ” 1 in 9 women in Canada is expected to develop breast cancer during her lifetime.” Today we are focusing on the genetic aspects of developing breast cancer in the body.
BRCA1 and BRCA2 genes – BRCA1 and BRCA 2 known, as a Breast Cancer Susceptibility Gene 1 and Breast Cancer Susceptibility Gene 2 are human genes and works as tumor suppressors.
How BRCA1 and BRCA2 connect to cancer? When any of those genes mutate, it causes DNA damage and it might not be able to repair properly, and as a results cell can develop additional genetic alterations. Inherited mutations in BRCA1 and BRCA2 then increase the risk of breast and ovarian cancer.
NOTE: BRCA1 and BRCA2 mutations can be inherited from a person’s mother or father. Anyone who has inherited a BRCA1 or BRCA2 mutation could be an increase risk of developing breast and ovarian cancer.
Breast cancer statistics – Breast Cancer Society of Canada has some shocking estimated figures in 2015.
An estimated 25,000 Canadian women will be diagnosed with breast cancer and 5,000 will die from it.
Approximately 68 Canadian women will be diagnosed with breast cancer every day.
Approximately 14 Canadian women will die of breast cancer every day.
1 in 9 woman is expected to develop breast cancer during her lifetime and 1 in 29 will die from it.
It is expected that 220 men will be diagnosed with breast cancer and 60 will die from it.
Who should go for the BRCA1 and BRCA2 gene test? – Anyone who has a family history that suggests the presence of the possible harmful mutation in BRCA1 and BRCA2 can go for the test. There are many people who were adopted and do not know their family history, they can go for the test as well. Ashkenazi Jewish ethnicity is one of highest risk of developing cancer; anyone from that community can do the test.
BRCA1 and BRCA2 testing gives you an opportunity to know about your risk of developing breast and ovarian cancer. Get tested today.
Step one – Our health consultants will discuss your medical and family history, explain the testing, answer any questions you may have and recommend the best test for you.
Step two – Samples are collected and sent to our lab for analysis. Specific genetic markers are screened to determine your genetic risk.
“DNA may also be collected through other means. Common forensic samples are hair (must have the root ball attached), mucous on a tissue, earwax and toothbrushes. However the cost will be on average $100 extra.”